Publications

Selected Publications

 

2026

• Zink A., Dai D., Wittich A., Henke M.-T., Pedrotti G., Heiduschka S., Santamaria G., Pentimalli T. M., Christian, Brueser Ch., Notopoulou S., Umar A. R., Zhaivoron A., Petersilie L., Jerred C., Bergmans J, Neu L. A., Schumacher F., Keller-Findeisen J., Rybak-Wolf A., Stach D.,…Prigione A. "Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy." Cell 2026 Mar 19;44(1):1591-1874. doi: 10.1016/j.cell.2026.02.008

 

2025

• Hartmann, C., Haferkamp, U., Appelt-Menzel, A., Barenberg, J., Brachner, A., Ehrhard, T., Feldhaus, J., Gerhartl, A., Hollemann, T., Kulka, L.A.M., Leckzik, S., Leu, J., Woo, M.S., Friese, M.A., Initiative ADN, Metzger, M., Neuhaus, W., Oerter, S., Olzscha, H., Pich, A., Riemann, D., Pless, O., Rujescu, D., Jung, M. (2026). "Brain capillary endothelial-like cells show altered barrier functionality and reduced transport of amyloid beta in late-onset Alzheimer disease." Fluids and Barriers of the CNS, 23(1):11. doi: 10.1186/s12987-025-00753-7
• Krieg, K., Materna-Reichelt, S., Naber, T., Rachad, F.Z., Kauven, P., Weller, A., Haferkamp, U., Wittich, A., Zaliani, A., Woo, M.S., Walkenhorst, M., Siegmund, M., Harberts, J., Zierold, R., Blick, R., Conze, C., Muschong, P., Miltner, D., Friese, M.A., Mezler, M., Siegmund, H., Evert, K., Krasemann, S., Gužvić, N.S., Klein, C.A., Werner-Klein, M., Wegener, J., Pless, O. "Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs." Cell Reports Methods,5(12):101236. doi: 10.1016/j.crmeth.2025.101236

 

2023

• Haferkamp U., Hartmann C., Abid C. L., Brachner A., Höchner A., Gerhartl A., Harwardt B., Leckzik S., Leu J., Metzger M., Nastainczyk-Wulf M., Neuhaus W., Oerter S., Pless O., Rujescu D., Jung M. T., & Appelt-Menzel A. (2023). "Human isogenic cells of the neurovascular unit exert transcriptomic cell type-specific effects on a blood-brain barrier in vitro model of late-onset Alzheimer disease." Fluids and Barriers of the Cns, 20(1). doi:10.1186/s12987-023-00471-y

 

2022

• Krasemann, S., Haferkamp, U., Pfefferle, S., Woo, M.S., Heinrich, F., Schweizer, M., Appelt-Menzel, A., Cubukova, A., Barenberg, J., Leu, J., Hartmann, K., Thies, E., Littau, J.L., Sepulveda-Falla, D., Zhang, L., Ton, K., Liang, Y., Matschke, J., Ricklefs, F., Sauvigny, T., Sperhake, J., Fitzek, A., Gerhartl, A., Brachner, A., Geiger, N., König, E.M., Bodem, J., Franzenburg, S., Franke, A., Moese, S., Müller, F.J., Geisslinger, G., Claussen, C., Kannt, A., Zaliani, A., Gribbon, P., Ondruschka, B., Neuhaus, W., Friese, M.A., Glatzel, M., Pless, O. (2022). The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2. Stem Cell Reports, 17(2), 307-320. doi:10.1016/j.stemcr.2021.12.011
• Zink A., Haferkamp U., Wittich A., Beller M., Pless O., & Prigione A. (2022). "High-content screening of mitochondrial polarization in neural cells derived from human pluripotent stem cells." STAR Protocols, 3(3), 101602. doi:10.1016/j.xpro.2022.101602