Fraunhofer Institute for Translational Medicine and Pharmacology ITMP

Immune diseases, such as rheumatism or psoriasis, are systemic diseases that often affect several organ systems simultaneously. An interdisciplinary approach is absolutely necessary for the optimal care of patients. This is implemented at Fraunhofer ITMP in the concept of the 4D Clinic. Professor Frank Behrens, deputy director of the institute, describes in the Fraunhofer podcast why the 4D Clinic is unique and what the concept can achieve for patients and research.

Hereditary angioedema (HAE) is a disorder in which one or more parts of the body become swollen. The triggers for HAE are unknown and is life threatening disorder, especially when the upper respiratory tract is affected. Current treatments for HAE include injections and infusions. In a Phase 2 clinical being run at the Universitätsklinikum Frankfurt, Charité - Universitätsmedizin Berlin and the Fraunhofer ITMP, it has been shown for the first time that an orally administered drug is effective against HAE. This therapy has the potential to overcome the issues relating the complicated route of administration for injections as well reduced cost.

The first Summer School of the Innovation Center »Innovative Therapeutics« (TheraNova) took place in Mainz, October 13 to October 14, 2022. Project updates were given by participating PhD students and clinician scientists from Johann Wolfgang Goethe University and the Fraunhofer Institutes ITMP and IGD, and invited speakers highlighted current developments in the fields of innovative therapeutics, personalized medicine and entrepreneurship.