Publikationen

Ausgewählte Publikationen

 

2025

• Haupt J, Keminer O, Neser C, Windshügel B, Wiltzsch V, Schmidt JR, Pliushcheuskaya P, Künze G, Scholz U, Müller C, Oliveira da Rocha GH, Biermann MK, Zdzieblo D, Metzger M, Schiefke I, Neurath MF, Siegmund B, Claussen C, Köhl U, Geisslinger G, Buchholz M, Kalkhof S, Lehmann J. "Novel aryl hydrocarbon receptor agonists as potential anti-inflammatory therapeutics: Identification and validation through drug repurposing." Biochem Pharmacol. 2025 Oct;240:117066. doi: 10.1016/j.bcp.2025.117066
• Carotenuto L, Keminer O, Carleo G, Zaliani A, Leo A, Citraro R, De Sarro G, Dirkx N, Kaji M, Weckhuysen S, Reinshagen J, Barrese V, Guida N, Ostacolo C, Miceli F, Gribbon P, Taglialatela M. "The fast-dissociating D2 antagonist antipsychotic JNJ-37822681 is a neuronal Kv7 channel opener: Potential repurposing for epilepsy treatment." Br J Pharmacol. 2025 Nov;182(22):5574-5595. doi: 10.1111/bph.70119
• Borsari C, Santarem N, Coertzen D, Mazzolari A, Corfu AI, Coelho C, Barbosa F, Tamborini L, Birkholtz LM, Raffellini L, Keminer O, Basilico N, Parapini S, Gul S, Cordeiro-da-Silva A, Conti P. "From pan-active to parasite-selective antiparasitic agents: A scaffold hopping approach." Eur J Med Chem. 2025 Dec 15;300:118095. doi: 10.1016/j.ejmech.2025.118095
• Huchting J, Weller A, Schweizer M, Brandt M, Heering J, Kuzikov M, Wolf M, Reinshagen J, Queisser MA, Gribbon P, Zaliani A, Pless O, Kannt A. "Optimization and Evaluation of Complementary Degrader Discovery Assays for Application in Screening." ACS Pharmacol Transl Sci. 2025 Jul 20;8(8):2600-2611. doi: 10.1021/acsptsci.5c00195
• Castillo-Aguilera OO, Depreux P, Halby L, Bailly C, Domínguez-Ramírez L, Gul S, Arimondo PB, Goossens L. "Design, synthesis and evaluation of pyrimidinobenzylamide and pyrimidinothiophenamide derivatives as inhibitors of DOT1L and related epigenetic targets DNMT3a, PRMT4 and other HMTs." RSC Med Chem. 2025 Jan 30;16(5):2159-2173. doi: 10.1039/d4md00899e

 

2024

• Gadiya Y., Shetty S., Hofmann-Apitius M., Gribbon P., & Zaliani A. (2024). "Exploring SureChEMBL from a drug discovery perspective." Scientific Data, 11(1). doi:10.1038/s41597-024-03371-4
• Jalencas X., Berg H., Espeland L. O., Sreeramulu S., Kinnen F., Richter C., Georgiou C., Yadrykhinsky V., Specker E., Jaudzems K., Miletic T., Harmel R., Gribbon P., Schwalbe H., Brenk R., Jirgensons A., Zaliani A., & Mestres J. (2024). "Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection." Rsc Medicinal Chemistry, 15(4). doi:10.1039/d3md00724c
• Kuzikov M., Reinshagen J., Wycisk K., Corona A., Esposito F., Malune P., Manelfi C., Iaconis D., Beccari A., Tramontano E., Nowotny M., Windshuegel B., Gribbon P., & Zaliani A. (2024). "Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex." Virus Research, 343. doi:10.1016/j.virusres.2024.199356

 

2023

• Schindler M., Siegerist F., Lange T., Simm S., Bach S. M., Klawitter M., Gehrig J., Gul S., & Endlich N. (2023). "A Novel High-Content Screening Assay Identified Belinostat as Protective in a FSGS-Like Zebrafish Model." Journal of the American Society of Nephrology, 34(12), 1977-1990. doi: 10.1681/Asn.0000000000000235